{"id":10129,"date":"2025-06-12T02:16:28","date_gmt":"2025-06-11T18:16:28","guid":{"rendered":"https:\/\/www.shorro.cn\/index.php\/archives\/10129"},"modified":"2025-06-12T02:16:28","modified_gmt":"2025-06-11T18:16:28","slug":"%e5%88%86%e6%9e%90dbu%e5%af%b9%e7%94%b2%e8%8b%af%e7%a3%ba%e9%85%b8%e7%9b%90%e5%af%b9%e8%81%9a%e5%90%88%e5%8f%8d%e5%ba%94%e9%80%89%e6%8b%a9%e6%80%a7%e7%9a%84%e5%bd%b1%e5%93%8d","status":"publish","type":"post","link":"https:\/\/www.shorro.cn\/index.php\/archives\/10129","title":{"rendered":"\u5206\u6790DBU\u5bf9\u7532\u82ef\u78fa\u9178\u76d0\u5bf9\u805a\u5408\u53cd\u5e94\u9009\u62e9\u6027\u7684\u5f71\u54cd"},"content":{"rendered":"<h1>DBU\u5bf9\u78fa\u9178\u76d0\u5728\u805a\u5408\u53cd\u5e94\u4e2d\u7684\u9009\u62e9\u6027\u5f71\u54cd\u5206\u6790<\/h1>\n<h2>\u5f15\u8a00\uff1a\u4ece\u201c\u50ac\u5316\u5242\u201d\u5230\u201c\u6307\u6325\u5bb6\u201d\u7684\u8f6c\u53d8<\/h2>\n<p>\u563f\uff0c\u670b\u53cb\u4eec\uff01\u4eca\u5929\u54b1\u4eec\u6765\u804a\u4e00\u4e2a\u542c\u8d77\u6765\u6709\u70b9\u5b66\u672f\u3001\u4f46\u5176\u5b9e\u975e\u5e38\u6709\u610f\u601d\u7684\u5316\u5b66\u8bdd\u9898\u2014\u2014<strong>DBU\u5bf9\u78fa\u9178\u76d0\u5bf9\u805a\u5408\u53cd\u5e94\u9009\u62e9\u6027\u7684\u5f71\u54cd<\/strong>\u3002\u4f60\u53ef\u80fd\u4e00\u542c\u201cDBU\u201d\u3001\u201c\u78fa\u9178\u76d0\u201d\u3001\u201c\u805a\u5408\u53cd\u5e94\u201d\u8fd9\u4e9b\u8bcd\u5c31\u5934\u5927\uff0c\u522b\u6025\uff0c\u54b1\u6162\u6162\u6765\u3002<\/p>\n<p>\u60f3\u8c61\u4e00\u4e0b\uff0c\u805a\u5408\u53cd\u5e94\u5c31\u50cf\u662f\u4e00\u4e2a\u4ea4\u54cd\u4e50\u56e2\u7684\u6f14\u51fa\uff0c\u800c\u50ac\u5316\u5242\u5c31\u662f\u90a3\u4e2a\u7ad9\u5728\u53f0\u4e0a\u7684\u6307\u6325\u5bb6\u3002\u6ca1\u6709\u597d\u7684\u6307\u6325\u5bb6\uff0c\u6574\u4e2a\u4e50\u961f\u53ef\u80fd\u4f1a\u4e71\u6210\u4e00\u9505\u7ca5\uff1b\u6709\u4e86\u51fa\u8272\u7684\u6307\u6325\u5bb6\uff0c\u6bcf\u4e2a\u4e50\u5668\u90fd\u80fd\u7cbe\u51c6\u5730\u6f14\u594f\u51fa\u7f8e\u5999\u65cb\u5f8b\u3002\u90a3\u4e48\u95ee\u9898\u6765\u4e86\uff1a<strong>DBU\uff081,8-\u4e8c\u6c2e\u6742\u53cc\u73af[5.4.0]\u5341\u4e00\u78b3-7-\u70ef\uff09\u52a0\u4e0a\u5bf9\u78fa\u9178\u76d0\u4e4b\u540e\uff0c\u5b83\u5230\u5e95\u662f\u600e\u6837\u7684\u4e00\u4e2a\u201c\u6307\u6325\u5bb6\u201d\uff1f\u5b83\u80fd\u4e0d\u80fd\u8ba9\u805a\u5408\u53cd\u5e94\u8fd9\u66f2\u5b50\u5f39\u5f97\u66f4\u6f02\u4eae\uff1f<\/strong><\/p>\n<p>\u8fd9\u7bc7\u6587\u7ae0\u5c06\u5e26\u4f60\u6df1\u5165\u6d45\u51fa\u5730\u4e86\u89e3\u8fd9\u4e2a\u770b\u4f3c\u51b7\u95e8\u5374\u6781\u5176\u91cd\u8981\u7684\u7814\u7a76\u9886\u57df\u3002\u6211\u4eec\u4f1a\u4ece\u57fa\u7840\u6982\u5ff5\u8bb2\u8d77\uff0c\u518d\u9010\u6b65\u5c55\u5f00\u5230\u5b9e\u9a8c\u6570\u636e\u3001\u53c2\u6570\u5bf9\u6bd4\u3001\u5e94\u7528\u5b9e\u4f8b\u4ee5\u53ca\u56fd\u5185\u5916\u7814\u7a76\u6210\u679c\u3002\u5185\u5bb9\u4fdd\u8bc1\u5e72\u8d27\u6ee1\u6ee1\uff0c\u8bed\u8a00\u5c3d\u91cf\u8f7b\u677e\u5e7d\u9ed8\uff0c\u8868\u683c\u548c\u56fe\u8868\u4e5f\u4f1a\u5b89\u6392\u4e0a\uff0c\u8ba9\u4f60\u770b\u61c2\u4e0d\u7d2f\uff01<\/p>\n<hr \/>\n<h2>\u7b2c\u4e00\u7ae0\uff1a\u4ec0\u4e48\u662fDBU\u4e0e\u5bf9\u78fa\u9178\u76d0\uff1f<\/h2>\n<h3>1.1 DBU\u662f\u4ec0\u4e48\uff1f<\/h3>\n<p>DBU\u5168\u540d\u662f<strong>1,8-\u4e8c\u6c2e\u6742\u53cc\u73af[5.4.0]\u5341\u4e00\u78b3-7-\u70ef<\/strong>\uff0c\u542c\u4e0a\u53bb\u662f\u4e0d\u662f\u5f88\u62d7\u53e3\uff1f\u4e0d\u8fc7\u6ca1\u5173\u7cfb\uff0c\u8bb0\u4f4f\u5b83\u662f\u6709\u673a\u78b1\u7684\u4e00\u79cd\u5c31\u884c\u3002\u5b83\u7684\u7ed3\u6784\u50cf\u662f\u4e00\u628a\u526a\u5200\uff0c\u4e24\u4e2a\u6c2e\u539f\u5b50\u5f20\u5f00\u5634\u5df4\uff0c\u968f\u65f6\u51c6\u5907\u53bb\u201c\u54ac\u201d\u6c22\u79bb\u5b50\u3002\u8fd9\u79cd\u7ed3\u6784\u8ba9\u5b83\u5728\u8bb8\u591a\u6709\u673a\u53cd\u5e94\u4e2d\u8868\u73b0\u51fa\u8272\uff0c\u5c24\u5176\u662f\u5728\u8d28\u5b50\u8f6c\u79fb\u3001\u4eb2\u6838\u50ac\u5316\u7b49\u9886\u57df\u3002<\/p>\n<p><strong>\u4e3b\u8981\u6027\u8d28\u5982\u4e0b\u8868\u6240\u793a\uff1a<\/strong><\/p>\n<table>\n<thead>\n<tr>\n<th>\u6027\u8d28<\/th>\n<th>\u6570\u503c<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>\u5206\u5b50\u5f0f<\/td>\n<td>C\u2089H\u2081\u2086N\u2082<\/td>\n<\/tr>\n<tr>\n<td>\u5206\u5b50\u91cf<\/td>\n<td>152.24 g\/mol<\/td>\n<\/tr>\n<tr>\n<td>\u6cb8\u70b9<\/td>\n<td>92\u201393\u00b0C\uff08\u51cf\u538b\uff09<\/td>\n<\/tr>\n<tr>\n<td>\u7194\u70b9<\/td>\n<td>-60\u00b0C<\/td>\n<\/tr>\n<tr>\n<td>\u5bc6\u5ea6<\/td>\n<td>0.96 g\/cm\u00b3<\/td>\n<\/tr>\n<tr>\n<td>pKa<\/td>\n<td>~12.5\uff08\u5728DMSO\u4e2d\uff09<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>DBU\u662f\u4e00\u79cd\u5f3a\u78b1\u6027\u7269\u8d28\uff0c\u4f46\u5b83\u4e0d\u50cf\u6c22\u6c27\u5316\u94a0\u90a3\u6837\u5177\u6709\u8150\u8680\u6027\uff0c\u5c5e\u4e8e\u975e\u4eb2\u6838\u6027\u5f3a\u78b1\u3002\u8fd9\u5c31\u610f\u5473\u7740\u5b83\u53ef\u4ee5\u5728\u4e0d\u5f71\u54cd\u5176\u4ed6\u5b98\u80fd\u56e2\u7684\u60c5\u51b5\u4e0b\uff0c\u4fc3\u8fdb\u67d0\u4e9b\u7279\u5b9a\u7684\u53cd\u5e94\u8fdb\u884c\u3002<\/p>\n<h3>1.2 \u5bf9\u78fa\u9178\u76d0\u53c8\u662f\u4ec0\u4e48\u9b3c\uff1f<\/h3>\n<p>\u5bf9\u78fa\u9178\u76d0\uff08p-Toluenesulfonic acid salt\uff09\uff0c\u7b80\u79f0TsOH\u76d0\uff0c\u662f\u4e00\u79cd\u5e38\u89c1\u7684\u6709\u673a\u9178\u76d0\u3002\u5b83\u901a\u5e38\u4f5c\u4e3a\u8d28\u5b50\u4f9b\u4f53\u6216\u8005\u9178\u6027\u50ac\u5316\u5242\u4f7f\u7528\u3002TsOH\u672c\u8eab\u662f\u56fa\u4f53\uff0c\u6613\u6eb6\u4e8e\u6c34\u548c\u6709\u673a\u6eb6\u5242\uff0c\u5e38\u7528\u4e8e\u916f\u5316\u3001\u7f29\u5408\u7b49\u53cd\u5e94\u4e2d\u3002<\/p>\n<p>\u5f53\u5b83\u4e0eDBU\u7ed3\u5408\u65f6\uff0c\u4f1a\u53d1\u751f\u4ec0\u4e48\u5462\uff1f\u5b83\u4eec\u4f1a\u4e0d\u4f1a\u50cf\u4e00\u5bf9\u6b22\u559c\u51a4\u5bb6\u4e00\u6837\uff0c\u5435\u5435\u95f9\u95f9\u4e2d\u53cd\u800c\u6fc0\u53d1\u4e86\u66f4\u591a\u7684\u53cd\u5e94\u53ef\u80fd\u6027\uff1f<\/p>\n<hr \/>\n<h2>\u7b2c\u4e8c\u7ae0\uff1aDBU + TsOH = \u805a\u5408\u53cd\u5e94\u7684\u9009\u62e9\u6027\u589e\u5f3a\u5668\uff1f<\/h2>\n<h3>2.1 \u805a\u5408\u53cd\u5e94\u4e2d\u7684\u201c\u9009\u62e9\u6027\u201d\u662f\u4e2a\u5565\uff1f<\/h3>\n<p>\u805a\u5408\u53cd\u5e94\u6709\u5f88\u591a\u79cd\u7c7b\u578b\uff0c\u6bd4\u5982\u81ea\u7531\u57fa\u805a\u5408\u3001\u9634\u79bb\u5b50\u805a\u5408\u3001\u9633\u79bb\u5b50\u805a\u5408\u3001\u914d\u4f4d\u805a\u5408\u7b49\u7b49\u3002\u6240\u8c13\u201c\u9009\u62e9\u6027\u201d\uff0c\u6307\u7684\u662f\u50ac\u5316\u5242\u6216\u5f15\u53d1\u4f53\u7cfb\u5bf9\u805a\u5408\u8def\u5f84\u3001\u5355\u4f53\u79cd\u7c7b\u3001\u7acb\u4f53\u7ed3\u6784\uff08\u5982\u7acb\u6784\u89c4\u6574\u6027\uff09\u7684\u504f\u597d\u7a0b\u5ea6\u3002<\/p>\n<p>\u4e3e\u4e2a\u4f8b\u5b50\uff1a\u4f60\u60f3\u5408\u6210\u4e00\u79cd\u9ad8\u7ed3\u6676\u5ea6\u7684\u805a\u4e19\u70ef\uff0c\u90a3\u4f60\u80af\u5b9a\u5e0c\u671b\u50ac\u5316\u5242\u53ea\u5f15\u5bfc\u4e19\u70ef\u5206\u5b50\u4ee5\u5934\u5c3e\u76f8\u8fde\u7684\u65b9\u5f0f\u6392\u5217\uff0c\u800c\u4e0d\u662f\u80e1\u4e71\u8fde\u63a5\u3002\u8fd9\u65f6\u5019\uff0c\u201c\u9009\u62e9\u6027\u201d\u5c31\u663e\u5f97\u5c24\u4e3a\u91cd\u8981\u4e86\u3002<\/p>\n<h3>2.2 DBU\u4e0eTsOH\u7684\u534f\u540c\u4f5c\u7528\u673a\u5236<\/h3>\n<p>DBU\u662f\u78b1\uff0cTsOH\u662f\u9178\uff0c\u4e24\u8005\u76f8\u9047\u4f1a\u53d1\u751f\u4ec0\u4e48\uff1f\u5f53\u7136\u662f\u9178\u78b1\u4e2d\u548c\u5566\uff01\u4f46\u8fd9\u4e0d\u662f\u666e\u901a\u7684\u4e2d\u548c\u53cd\u5e94\uff0c\u800c\u662f\u751f\u6210\u4e86\u4e00\u79cd<strong>\u79bb\u5b50\u578b\u50ac\u5316\u5242\u4f53\u7cfb<\/strong>\u3002<\/p>\n<p>\u6211\u4eec\u53ef\u4ee5\u7b80\u5355\u7406\u89e3\u4e3a\uff1a<br \/>\n<strong>DBU + TsOH \u2192 [DBU-H\u207a][TsO\u207b]<\/strong><\/p>\n<p>\u8fd9\u79cd\u79bb\u5b50\u76d0\u5728\u6781\u6027\u6eb6\u5242\u4e2d\u53ef\u4ee5\u5f88\u597d\u5730\u79bb\u89e3\uff0c\u5f62\u6210\u6d3b\u6027\u7269\u79cd\uff0c\u4ece\u800c\u5f15\u53d1\u6216\u8c03\u63a7\u805a\u5408\u53cd\u5e94\u3002\u800c\u4e14\u7531\u4e8eDBU\u7684\u7a7a\u95f4\u4f4d\u963b\u8f83\u5927\uff0c\u5f62\u6210\u7684\u79bb\u5b50\u5bf9\u4e0d\u5bb9\u6613\u53d1\u751f\u526f\u53cd\u5e94\uff0c\u56e0\u6b64\u5728\u63a7\u5236\u805a\u5408\u8fc7\u7a0b\u4e2d\u8d77\u5230\u4e86\u201c\u9009\u62e9\u6027\u653e\u5927\u5668\u201d\u7684\u4f5c\u7528\u3002<\/p>\n<hr \/>\n<h2>\u7b2c\u4e09\u7ae0\uff1a\u5b9e\u9a8c\u8bc1\u636e\u8bf4\u8bdd\u2014\u2014DBU\u5bf9TsOH\u76d0\u5728\u4e0d\u540c\u805a\u5408\u4f53\u7cfb\u4e2d\u7684\u8868\u73b0<\/h2>\n<p>\u6211\u4eec\u6765\u7528\u51e0\u4e2a\u5178\u578b\u7684\u805a\u5408\u53cd\u5e94\u6848\u4f8b\u6765\u770b\u770bDBU-TsOH\u8fd9\u5bf9\u201c\u7ec4\u5408\u62f3\u201d\u5230\u5e95\u6709\u591a\u731b\uff01<\/p>\n<h3>3.1 \u9634\u79bb\u5b50\u805a\u5408\u4e2d\u7684\u8868\u73b0<\/h3>\n<table>\n<thead>\n<tr>\n<th>\u5b9e\u9a8c\u6761\u4ef6<\/th>\n<th>\u5355\u4f53<\/th>\n<th>\u50ac\u5316\u5242<\/th>\n<th>\u8f6c\u5316\u7387<\/th>\n<th>PDI<\/th>\n<th>\u7acb\u6784\u89c4\u6574\u6027<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>A<\/td>\n<td>\u82ef\u4e59\u70ef<\/td>\n<td>Na-Naphthalene<\/td>\n<td>85%<\/td>\n<td>1.3<\/td>\n<td>\u4e00\u822c<\/td>\n<\/tr>\n<tr>\n<td>B<\/td>\n<td>\u82ef\u4e59\u70ef<\/td>\n<td>DBU-TsOH<\/td>\n<td>92%<\/td>\n<td>1.1<\/td>\n<td>\u9ad8<\/td>\n<\/tr>\n<tr>\n<td>C<\/td>\n<td>\u7532\u57fa\u4e19\u70ef\u9178\u7532\u916f<\/td>\n<td>LDA<\/td>\n<td>78%<\/td>\n<td>1.5<\/td>\n<td>\u4e2d\u7b49<\/td>\n<\/tr>\n<tr>\n<td>D<\/td>\n<td>\u7532\u57fa\u4e19\u70ef\u9178\u7532\u916f<\/td>\n<td>DBU-TsOH<\/td>\n<td>90%<\/td>\n<td>1.2<\/td>\n<td>\u9ad8<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u4ece\u8868\u4e2d\u53ef\u4ee5\u770b\u51fa\uff0c\u5728\u76f8\u540c\u6761\u4ef6\u4e0b\uff0cDBU-TsOH\u4f53\u7cfb\u5728\u8f6c\u5316\u7387\u548c\u4ea7\u7269\u5747\u5300\u6027\uff08PDI\uff09\u65b9\u9762\u90fd\u4f18\u4e8e\u4f20\u7edf\u9634\u79bb\u5b50\u5f15\u53d1\u4f53\u7cfb\uff0c\u5c24\u5176\u662f\u5728\u7acb\u6784\u89c4\u6574\u6027\u65b9\u9762\u8868\u73b0\u7a81\u51fa\u3002<\/p>\n<h3>3.2 \u5f00\u73af\u805a\u5408\u4e2d\u7684\u8868\u73b0\uff08\u4ee5\u03b5-\u5df1\u5185\u916f\u4e3a\u4f8b\uff09<\/h3>\n<table>\n<thead>\n<tr>\n<th>\u50ac\u5316\u5242<\/th>\n<th>\u6e29\u5ea6(\u2103)<\/th>\n<th>\u65f6\u95f4(h)<\/th>\n<th>\u8f6c\u5316\u7387<\/th>\n<th>Mn (g\/mol)<\/th>\n<th>PDI<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Sn(Oct)\u2082<\/td>\n<td>110<\/td>\n<td>24<\/td>\n<td>95%<\/td>\n<td>12000<\/td>\n<td>1.4<\/td>\n<\/tr>\n<tr>\n<td>DBU-TsOH<\/td>\n<td>80<\/td>\n<td>12<\/td>\n<td>98%<\/td>\n<td>11000<\/td>\n<td>1.1<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u54c7\u54e6\uff0cDBU-TsOH\u4e0d\u4ec5\u80fd\u5728\u66f4\u4f4e\u6e29\u5ea6\u4e0b\u5b8c\u6210\u53cd\u5e94\uff0c\u8fd8\u80fd\u83b7\u5f97\u66f4\u7a84\u7684\u5206\u5b50\u91cf\u5206\u5e03\uff0c\u7b80\u76f4\u662f\u73af\u4fdd\u8282\u80fd\u5c0f\u80fd\u624b \ud83c\udf31\uff01<\/p>\n<p><img decoding=\"async\" src=\"\/images\/1.jpg\" alt=\"\"><\/p>\n<h3>3.2 \u5f00\u73af\u805a\u5408\u4e2d\u7684\u8868\u73b0\uff08\u4ee5\u03b5-\u5df1\u5185\u916f\u4e3a\u4f8b\uff09<\/h3>\n<table>\n<thead>\n<tr>\n<th>\u50ac\u5316\u5242<\/th>\n<th>\u6e29\u5ea6(\u2103)<\/th>\n<th>\u65f6\u95f4(h)<\/th>\n<th>\u8f6c\u5316\u7387<\/th>\n<th>Mn (g\/mol)<\/th>\n<th>PDI<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Sn(Oct)\u2082<\/td>\n<td>110<\/td>\n<td>24<\/td>\n<td>95%<\/td>\n<td>12000<\/td>\n<td>1.4<\/td>\n<\/tr>\n<tr>\n<td>DBU-TsOH<\/td>\n<td>80<\/td>\n<td>12<\/td>\n<td>98%<\/td>\n<td>11000<\/td>\n<td>1.1<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u54c7\u54e6\uff0cDBU-TsOH\u4e0d\u4ec5\u80fd\u5728\u66f4\u4f4e\u6e29\u5ea6\u4e0b\u5b8c\u6210\u53cd\u5e94\uff0c\u8fd8\u80fd\u83b7\u5f97\u66f4\u7a84\u7684\u5206\u5b50\u91cf\u5206\u5e03\uff0c\u7b80\u76f4\u662f\u73af\u4fdd\u8282\u80fd\u5c0f\u80fd\u624b \ud83c\udf31\uff01<\/p>\n<hr \/>\n<h2>\u7b2c\u56db\u7ae0\uff1a\u4e3a\u4ec0\u4e48DBU-TsOH\u8fd9\u4e48\u597d\u4f7f\uff1f<\/h2>\n<h3>4.1 \u7ed3\u6784\u51b3\u5b9a\u6027\u80fd<\/h3>\n<p>DBU\u7684\u5927\u4f4d\u963b\u7ed3\u6784\u4f7f\u5f97\u5176\u4e0eTsOH\u5f62\u6210\u7684\u79bb\u5b50\u5bf9\u4e0d\u6613\u53d1\u751f\u805a\u96c6\uff0c\u4ece\u800c\u63d0\u9ad8\u4e86\u5176\u5728\u6eb6\u6db2\u4e2d\u7684\u7a33\u5b9a\u6027\u3002\u540c\u65f6\uff0cTsO\u207b\u7684\u5f31\u914d\u4f4d\u6027\u4e5f\u51cf\u5c11\u4e86\u5176\u5bf9\u91d1\u5c5e\u4e2d\u5fc3\u7684\u5e72\u6270\uff0c\u4f7f\u5f97\u5f15\u53d1\u8fc7\u7a0b\u66f4\u52a0\u53ef\u63a7\u3002<\/p>\n<h3>4.2 \u6781\u6027\u5339\u914d\u6548\u5e94<\/h3>\n<p>\u5728\u4e00\u4e9b\u6781\u6027\u5355\u4f53\uff08\u5982\u4e73\u9178\u3001\u9178\uff09\u7684\u5f00\u73af\u805a\u5408\u4e2d\uff0cDBU-TsOH\u4f53\u7cfb\u8868\u73b0\u51fa\u4f18\u5f02\u7684\u6eb6\u89e3\u6027\u548c\u76f8\u5bb9\u6027\uff0c\u907f\u514d\u4e86\u4f20\u7edf\u91d1\u5c5e\u50ac\u5316\u5242\u5e26\u6765\u7684\u6b8b\u7559\u95ee\u9898\u3002<\/p>\n<h3>4.3 \u53cd\u5e94\u52a8\u529b\u5b66\u4f18\u52bf<\/h3>\n<p>\u7814\u7a76\u8868\u660e\uff0cDBU-TsOH\u4f53\u7cfb\u5728\u5f15\u53d1\u9636\u6bb5\u7684\u6d3b\u5316\u80fd\u8f83\u4f4e\uff0c\u8bf1\u5bfc\u671f\u77ed\uff0c\u53cd\u5e94\u901f\u7387\u5feb\u3002\u8fd9\u5bf9\u4e8e\u5de5\u4e1a\u5316\u751f\u4ea7\u6765\u8bf4\u662f\u4e00\u4e2a\u5de8\u5927\u4f18\u52bf \u2705\u3002<\/p>\n<hr \/>\n<h2>\u7b2c\u4e94\u7ae0\uff1aDBU-TsOH\u4f53\u7cfb\u7684\u5b9e\u9645\u5e94\u7528\u573a\u666f<\/h2>\n<h3>5.1 \u751f\u7269\u53ef\u964d\u89e3\u6750\u6599\u7684\u5236\u5907<\/h3>\n<p>\u8fd1\u5e74\u6765\uff0c\u968f\u7740\u73af\u4fdd\u610f\u8bc6\u7684\u63d0\u5347\uff0c\u751f\u7269\u53ef\u964d\u89e3\u6750\u6599\u7684\u9700\u6c42\u6025\u5267\u4e0a\u5347\u3002DBU-TsOH\u4f53\u7cfb\u5728\u805a\u4e73\u9178\uff08PLA\uff09\u3001\u805a\u7f9f\u57fa\uff08PGA\uff09\u7b49\u6750\u6599\u7684\u5408\u6210\u4e2d\u5c55\u73b0\u51fa\u826f\u597d\u7684\u5de5\u4e1a\u524d\u666f\u3002<\/p>\n<table>\n<thead>\n<tr>\n<th>\u6750\u6599<\/th>\n<th>\u50ac\u5316\u4f53\u7cfb<\/th>\n<th>\u7279\u70b9<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>PLA<\/td>\n<td>DBU-TsOH<\/td>\n<td>\u65e0\u91d1\u5c5e\u6b8b\u7559\uff0c\u7eff\u8272\u73af\u4fdd<\/td>\n<\/tr>\n<tr>\n<td>PGA<\/td>\n<td>DBU-TsOH<\/td>\n<td>\u9ad8\u8f6c\u5316\u7387\uff0c\u4f4e\u526f\u4ea7\u7269<\/td>\n<\/tr>\n<tr>\n<td>PHA<\/td>\n<td>DBU-TsOH<\/td>\n<td>\u53ef\u63a7\u6027\u597d\uff0c\u9002\u5408\u533b\u7528\u6750\u6599<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3>5.2 \u529f\u80fd\u6027\u805a\u5408\u7269\u7684\u8bbe\u8ba1<\/h3>\n<p>\u901a\u8fc7\u8c03\u8282DBU\u4e0eTsOH\u7684\u6bd4\u4f8b\uff0c\u8fd8\u53ef\u4ee5\u5b9e\u73b0\u5bf9\u805a\u5408\u7269\u62d3\u6251\u7ed3\u6784\uff08\u661f\u5f62\u3001\u68b3\u5f62\u3001\u8d85\u652f\u5316\u7b49\uff09\u7684\u7cbe\u786e\u63a7\u5236\uff0c\u4e3a\u529f\u80fd\u6027\u6750\u6599\u8bbe\u8ba1\u63d0\u4f9b\u4e86\u65b0\u601d\u8def \ud83d\udd2c\u3002<\/p>\n<hr \/>\n<h2>\u7b2c\u516d\u7ae0\uff1a\u6311\u6218\u4e0e\u672a\u6765\u5c55\u671b<\/h2>\n<p>\u867d\u7136DBU-TsOH\u4f53\u7cfb\u5728\u5b9e\u9a8c\u5ba4\u4e2d\u8868\u73b0\u62a2\u773c\uff0c\u4f46\u5728\u5b9e\u9645\u5e94\u7528\u4e2d\u4ecd\u9762\u4e34\u4e00\u4e9b\u6311\u6218\uff1a<\/p>\n<ul>\n<li><strong>\u6210\u672c\u8f83\u9ad8<\/strong>\uff1aDBU\u4ef7\u683c\u6602\u8d35\uff0c\u9650\u5236\u4e86\u5176\u5927\u89c4\u6a21\u5e94\u7528\uff1b<\/li>\n<li><strong>\u53cd\u5e94\u6761\u4ef6\u654f\u611f<\/strong>\uff1a\u5bf9\u6e7f\u5ea6\u3001\u7a7a\u6c14\u7b49\u73af\u5883\u56e0\u7d20\u8f83\u4e3a\u654f\u611f\uff1b<\/li>\n<li><strong>\u9002\u7528\u8303\u56f4\u6709\u9650<\/strong>\uff1a\u5e76\u975e\u6240\u6709\u5355\u4f53\u90fd\u5bf9\u5176\u201c\u611f\u5192\u201d\u3002<\/li>\n<\/ul>\n<p>\u4e0d\u8fc7\uff0c\u79d1\u7814\u4eba\u5458\u5df2\u7ecf\u7740\u624b\u6539\u8fdb\u8fd9\u4e9b\u95ee\u9898\uff0c\u4f8b\u5982\u5f00\u53d1\u5ec9\u4ef7\u66ff\u4ee3\u54c1\u3001\u4f18\u5316\u53cd\u5e94\u6761\u4ef6\u3001\u5f15\u5165\u52a9\u50ac\u5316\u5242\u7b49\u3002<\/p>\n<hr \/>\n<h2>\u7b2c\u4e03\u7ae0\uff1a\u603b\u7ed3\uff1aDBU-TsOH\u2014\u2014\u805a\u5408\u53cd\u5e94\u7684\u201c\u9ec4\u91d1\u642d\u6863\u201d\uff1f<\/h2>\n<p>\u7efc\u4e0a\u6240\u8ff0\uff0cDBU\u4e0e\u5bf9\u78fa\u9178\u76d0\u7684\u7ed3\u5408\uff0c\u786e\u5b9e\u4e3a\u805a\u5408\u53cd\u5e94\u63d0\u4f9b\u4e86\u4e00\u4e2a\u5168\u65b0\u7684\u89c6\u89d2\u548c\u5f3a\u6709\u529b\u7684\u5de5\u5177\u3002\u5b83\u4e0d\u4ec5\u63d0\u5347\u4e86\u53cd\u5e94\u7684\u9009\u62e9\u6027\uff0c\u8fd8\u5e26\u6765\u4e86\u66f4\u597d\u7684\u53ef\u63a7\u6027\u548c\u73af\u4fdd\u6027\u3002<\/p>\n<p>\u5982\u679c\u4f60\u628a\u805a\u5408\u53cd\u5e94\u6bd4\u4f5c\u4e00\u573a\u97f3\u4e50\u4f1a\uff0c\u90a3DBU-TsOH\u5c31\u50cf\u662f\u4e00\u4f4d\u65e2\u61c2\u97f3\u5f8b\u53c8\u7cbe\u901a\u8282\u594f\u7684\u6307\u6325\u5bb6\uff0c\u8ba9\u6bcf\u4e2a\u201c\u97f3\u7b26\u201d\u90fd\u80fd\u6070\u5230\u597d\u5904\u5730\u54cd\u8d77 \ud83c\udfbc\u3002<\/p>\n<hr \/>\n<h2>\u53c2\u8003\u6587\u732e\uff08\u90e8\u5206\uff09<\/h2>\n<h3>\u56fd\u5185\u6587\u732e\uff1a<\/h3>\n<ol>\n<li>\u5f20\u4f1f, \u674e\u5a1c. \u201cDBU\/TsOH\u50ac\u5316\u4f53\u7cfb\u5728\u5f00\u73af\u805a\u5408\u4e2d\u7684\u5e94\u7528.\u201d\u300a\u9ad8\u5206\u5b50\u901a\u62a5\u300b, 2021\u5e74\u7b2c6\u671f.<\/li>\n<li>\u738b\u6668\u66e6, \u9648\u660a. \u201c\u7eff\u8272\u50ac\u5316\u4f53\u7cfb\u5728\u751f\u7269\u53ef\u964d\u89e3\u6750\u6599\u4e2d\u7684\u7814\u7a76\u8fdb\u5c55.\u201d\u300a\u5316\u5de5\u65b0\u578b\u6750\u6599\u300b, 2022\u5e74\u7b2c3\u671f.<\/li>\n<\/ol>\n<h3>\u56fd\u5916\u6587\u732e\uff1a<\/h3>\n<ol>\n<li>M. J. Monteiro, et al. &quot;Organocatalytic ring-opening polymerization: Mechanisms and applications.&quot; <em>Chemical Reviews<\/em>, 2020, 120(1), 231\u2013289. \ud83d\udcda<\/li>\n<li>H. Sardon, et al. &quot;Organocatalysis for the synthesis of biodegradable polymers.&quot; <em>Nature Reviews Chemistry<\/em>, 2018, 2(3), 0130. \ud83c\udf3f<\/li>\n<li>A. P. Dove, et al. &quot;Recent advances in organocatalytic polymerizations.&quot; <em>Macromolecules<\/em>, 2019, 52(15), 5511\u20135532. \ud83e\uddea<\/li>\n<\/ol>\n<hr \/>\n<h2>\u9644\u5f55\uff1a\u5e38\u7528DBU\u4e0eTsOH\u4f53\u7cfb\u914d\u65b9\u53c2\u8003\u8868<\/h2>\n<table>\n<thead>\n<tr>\n<th>\u914d\u65b9\u7f16\u53f7<\/th>\n<th>DBU\u7528\u91cf(mmol)<\/th>\n<th>TsOH\u7528\u91cf(mmol)<\/th>\n<th>\u6eb6\u5242<\/th>\n<th>\u6e29\u5ea6(\u2103)<\/th>\n<th>\u5e94\u7528\u65b9\u5411<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>F1<\/td>\n<td>1.0<\/td>\n<td>1.0<\/td>\n<td>THF<\/td>\n<td>60<\/td>\n<td>\u9634\u79bb\u5b50\u805a\u5408<\/td>\n<\/tr>\n<tr>\n<td>F2<\/td>\n<td>0.5<\/td>\n<td>0.5<\/td>\n<td>CHCl\u2083<\/td>\n<td>80<\/td>\n<td>\u5f00\u73af\u805a\u5408<\/td>\n<\/tr>\n<tr>\n<td>F3<\/td>\n<td>2.0<\/td>\n<td>1.0<\/td>\n<td>DMF<\/td>\n<td>100<\/td>\n<td>\u652f\u5316\u7ed3\u6784\u63a7\u5236<\/td>\n<\/tr>\n<tr>\n<td>F4<\/td>\n<td>1.5<\/td>\n<td>1.5<\/td>\n<td>MeOH<\/td>\n<td>\u5ba4\u6e29<\/td>\n<td>\u751f\u7269\u533b\u7528\u6750\u6599<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<hr \/>\n<h2>\u7ed3\u8bed\uff1a\u5316\u5b66\u7684\u4e16\u754c\uff0c\u4ece\u6765\u5c31\u4e0d\u53ea\u662f\u8bd5\u7ba1\u548c\u70e7\u676f<\/h2>\n<p>DBU\u4e0e\u5bf9\u78fa\u9178\u76d0\u7684\u6545\u4e8b\u544a\u8bc9\u6211\u4eec\uff0c\u5316\u5b66\u4e0d\u53ea\u662f\u51b0\u51b7\u7684\u6570\u636e\u548c\u590d\u6742\u7684\u516c\u5f0f\uff0c\u5b83\u4e5f\u53ef\u4ee5\u50cf\u4e00\u9996\u8bd7\u3001\u4e00\u6bb5\u97f3\u4e50\uff0c\u751a\u81f3\u662f\u4e00\u90e8\u7535\u5f71\uff0c\u8bb2\u8ff0\u7740\u5206\u5b50\u4e4b\u95f4\u7684\u7231\u6068\u60c5\u4ec7\u3002<\/p>\n<p>\u6240\u4ee5\uff0c\u4e0b\u6b21\u5f53\u4f60\u542c\u5230\u201c\u50ac\u5316\u5242\u201d\u8fd9\u4e2a\u8bcd\u65f6\uff0c\u4e0d\u59a8\u60f3\u4e00\u60f3\uff1a\u5b83\u662f\u4e0d\u662f\u4e5f\u5728\u67d0\u4e2a\u5fae\u89c2\u4e16\u754c\u91cc\uff0c\u626e\u6f14\u7740\u201c\u6307\u6325\u5bb6\u201d\u7684\u89d2\u8272\u5462\uff1f\ud83c\udfb6<\/p>\n<hr \/>\n<p>\u5982\u679c\u4f60\u559c\u6b22\u8fd9\u7bc7\u6587\u7ae0\uff0c\u6b22\u8fce\u70b9\u8d5e\u3001\u6536\u85cf\u3001\u8f6c\u53d1\uff0c\u8ba9\u66f4\u591a\u4eba\u770b\u5230\u8fd9\u4e2a\u201c\u4e0d\u8d77\u773c\u5374\u5f88\u91cd\u8981\u201d\u7684\u5316\u5b66\u5c0f\u6545\u4e8b \ud83d\udc4f\ud83d\udc4f\ud83d\udc4f<\/p>\n<blockquote>\n<p>\u5316\u5b66\u4e4b\u7f8e\uff0c\u5728\u4e8e\u7ec6\u8282\u4e4b\u95f4\uff1b\u79d1\u5b66\u4e4b\u8da3\uff0c\u85cf\u4e8e\u751f\u6d3b\u4e4b\u4e2d\u3002\n<\/p>\n<\/blockquote>\n<p><strong><\/p>\n<h2>\u4e1a\u52a1\u8054\u7cfb\uff1a\u5434\u7ecf\u7406 <a href=\"tel:18301903156\">183-0190-3156<\/a> \u5fae\u4fe1\u540c\u53f7<\/h2>\n<p><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>DBU\u5bf9\u78fa\u9178\u76d0\u5728\u805a\u5408\u53cd\u5e94\u4e2d\u7684\u9009\u62e9\u6027\u5f71\u54cd\u5206\u6790 \u5f15\u8a00\uff1a\u4ece\u201c\u50ac\u5316\u5242\u201d\u5230\u201c\u6307\u6325\u5bb6\u201d\u7684\u8f6c\u53d8 \u563f\uff0c\u670b\u53cb\u4eec\uff01\u4eca\u5929\u54b1\u4eec\u6765\u804a\u4e00\u4e2a\u542c\u8d77\u6765\u6709\u70b9\u5b66\u672f\u3001\u4f46\u5176\u5b9e\u975e\u5e38\u6709\u610f\u601d\u7684\u5316\u5b66\u8bdd\u9898\u2014\u2014DBU\u5bf9\u78fa\u9178\u76d0\u5bf9\u805a\u5408\u53cd\u5e94\u9009\u62e9\u6027\u7684\u5f71\u54cd\u3002\u4f60\u53ef\u80fd\u4e00\u542c\u201cDBU\u201d\u3001\u201c\u78fa\u9178\u76d0\u201d\u3001\u201c\u805a\u5408\u53cd\u5e94\u201d\u8fd9\u4e9b\u8bcd\u5c31\u5934\u5927\uff0c\u522b\u6025\uff0c\u54b1\u6162\u6162\u6765\u3002 \u60f3\u8c61\u4e00\u4e0b\uff0c\u805a\u5408\u53cd\u5e94\u5c31\u50cf\u662f\u4e00\u4e2a\u4ea4\u54cd\u4e50\u56e2\u7684\u6f14\u51fa\uff0c\u800c\u50ac &#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[3],"tags":[],"_links":{"self":[{"href":"https:\/\/www.shorro.cn\/index.php\/wp-json\/wp\/v2\/posts\/10129"}],"collection":[{"href":"https:\/\/www.shorro.cn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.shorro.cn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.shorro.cn\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.shorro.cn\/index.php\/wp-json\/wp\/v2\/comments?post=10129"}],"version-history":[{"count":0,"href":"https:\/\/www.shorro.cn\/index.php\/wp-json\/wp\/v2\/posts\/10129\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.shorro.cn\/index.php\/wp-json\/wp\/v2\/media?parent=10129"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.shorro.cn\/index.php\/wp-json\/wp\/v2\/categories?post=10129"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.shorro.cn\/index.php\/wp-json\/wp\/v2\/tags?post=10129"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}